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Mir-592 microRNA precursor family : ウィキペディア英語版 | Mir-592 microRNA precursor family In molecular biology mir-592 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. ==Expression in cancers== Significantly altered expression of miR-592 has been observed between tumours deficient and proficient for mismatch repair in colon cancer.〔 〕 Expression levels are lower in the proficient form compared to the deficient, with a more than two-fold change.〔 〕 This altered expression has been proposed to reflect a reversion to regulatory programs seen in earlier undifferentiated and proliferative developmental states. miR-592 expression is also altered in hepatocellular carcinoma; it has been shown to be downregulated along with nine other microRNAs.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Mir-592 microRNA precursor family」の詳細全文を読む
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